Road trips through
Missouri
27 road-trip plans across 6 cities.
Plan a Missouri road trip →Grab a hand-curated guide
Love this plan? Our premium itineraries go deeper — vetted stops, timing, and local secrets, ready to download and take on the road.
Cities travelers visit in Missouri
Sorted by how often they show up in road-trip plans.
Trips through Missouri
The Great American Music & Culture Road Trip: Denver to New Orleans
10 Days · Convertible · Kansas City → St. Louis → Nashville → Memphis → New Orleans
Route 66 Family Road Trip: Costa Mesa to Monett, MO
Cowboys, Craters & Cadillacs — 10 Days on the I-40 Corridor with Toddlers & a Tiny Traveler
Route 66 Family Road Trip: Costa Mesa, CA → Monett, MO
Cowboys, Dinosaurs & Classic Roadside America with Toddlers & a Baby
Route 66 Family Road Trip: Costa Mesa, CA → Monett, MO
Cowboys, Craters & Cadillacs — 10 Days on America's Mother Road with Littles in Tow
San Diego to Waldo, Ohio: Grand Canyon, Desert Southwest & Heartland Road Trip
10 Days of Big Skies, Canyon Rims & Family in the Midwest — Solo in a Honda Ridgeline
Route 66 Road Trip: Chicago to Phoenix
The Mother Road in 5 Days — Arches, Oddities & Open Desert
Route 66 End-to-End: Chicago to Santa Monica on Two Harleys
2,400 Miles of Asphalt, Americana, and a Las Vegas Detour
Route 66 Road Trip: Chicago to Phoenix
5 Days of Neon Signs, Quirky Stops & Wide-Open Skies on America's Mother Road
Ozarks Road Trip: Florida to the Hills & Hollows
10 Days of Scenic Drives, Small-Town Charm, and Roadside Magic Through Arkansas & Missouri
Heartland to Hollows: A Family Road Trip Through Kentucky, Tennessee & Arkansas
Lincoln, NE → Ark Encounter → Pigeon Forge → Hot Springs → Home | 7 Days, ~2,400 Miles
Toronto to Terrace BC: The Big Drive West
6 Days, ~3,200 Miles, BBQ, Big Skies & a Moving Adventure Across North America
Route 66 Family Road Trip: Costa Mesa to Monett, MO
Cowboys, Craters & Cadillacs — 10 Days on the Mother Road with Three Little Kids
Ready to map yours?
Plan my road trip →